Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

| Client | URL | |---|---| | Claude Code, Claude Desktop, Claude.ai connectors | https://mcp.appendix.com/mcp | | Anthropic Messages API (mcp_servers) | https://mcp.appendix.com/mcp |

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

| Tool | Description | |------|-------------| | search_knowledge_base | Search medical literature and treatment guidelines | | submit_encounter | Submit a clinical letter for physician review | | list_conditions | List available conditions and medications |

Development

npm install
npm run build
npm start

Watch mode:

npm run dev

Environment Variables

| Variable | Default | Description | |----------|---------|-------------| | API_BASE_URL | https://api.appendix.com | Appendix API base URL | | PORT | 3001 | HTTP listener port |

Endpoints

| Method | Path | Purpose | |---|---|---| | GET | /health | Render health probe | | POST GET DELETE | /mcp | Streamable HTTP transport (stateless mode) |

Appendix